BDBM50545647 CHEMBL4643358

SMILES O=C(CC#N)N1CCCC2CN(CC12)c1ncnc2[nH]ccc12

InChI Key InChIKey=CZQVWXNUAIAMTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50545647   

TargetTyrosine-protein kinase JAK3(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50545647(CHEMBL4643358)
Affinity DataIC50: 200nMAssay Description:Inhibition of human JAK3 (780 to end residues) expressed in baculovirus infected Sf9 cells using TK-substrate-biotin as substrate incubated for 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50545647(CHEMBL4643358)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full-length human Lck using TK-substrate-biotin as substrate incubated for 60 mins in presence of AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed