BDBM50545935 CHEMBL4741779

SMILES Fc1cccc(c1)-c1nc2sccn2c1-c1ccnc(NCCNC(=O)c2ccccc2)n1

InChI Key InChIKey=WKJXMYQEHKAEQS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50545935   

TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50545935(CHEMBL4741779)
Affinity DataIC50: 312nMAssay Description:Inhibition of human CRAF using MEK1 as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50545935(CHEMBL4741779)
Affinity DataIC50: 37nMAssay Description:Inhibition of human BRAF V600E mutant using MEK1 as substrate by [gamma-34P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50545935(CHEMBL4741779)
Affinity DataIC50: 162nMAssay Description:Inhibition of human BRAF using MEK1 as substrate by [gamma-34P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed