BDBM50545939 CHEMBL4794141

SMILES Fc1cccc(c1)-c1nc2sccn2c1-c1ccnc(NCCCNS(=O)(=O)c2ccc(cc2)C(F)(F)F)n1

InChI Key InChIKey=NYHSOWXTUFLOAT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50545939   

TargetSerine/threonine-protein kinase B-raf(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50545939(CHEMBL4794141)
Affinity DataIC50: 26nMAssay Description:Inhibition of human BRAF V600E mutant using MEK1 as substrate by [gamma-34P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50545939(CHEMBL4794141)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CRAF using MEK1 as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
National Research Centre (Nrc)

Curated by ChEMBL
LigandPNGBDBM50545939(CHEMBL4794141)
Affinity DataIC50: 63nMAssay Description:Inhibition of human BRAF using MEK1 as substrate by [gamma-34P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed