BDBM50546037 CHEMBL4786942

SMILES C[C@H]1CN(C[C@@H](C)O1)S(=O)(=O)c1ccc(Cl)c(COc2cccc3c(cc(C)nc23)C(F)(F)F)c1Cl

InChI Key InChIKey=ACRHHDXGVDIGOK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50546037   

TargetNuclear receptor ROR-gamma(Human)
Inventiva

Curated by ChEMBL
LigandPNGBDBM50546037(CHEMBL4786942)
Affinity DataEC50:  220nMAssay Description:Inverse agonist activity at pSG5GAL4-DBD/LBD fused human RORgamma receptor expressed in COS7 cells co-expressing 5 copies of GAL4 response element af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed