BDBM50546162 CHEMBL4752466

SMILES Cc1cccc(c1)-c1nnc(o1)N1CCN(CC1)c1ccccn1

InChI Key InChIKey=BCPJRBVIGIXBMJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50546162   

TargetBeta-secretase 1(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50546162(CHEMBL4752466)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of human BACE-1 using MOCA-SEV-NL-DAEFR-DNP-RR as substrate preincubated with substrate followed by enzyme addition by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50546162(CHEMBL4752466)
Affinity DataIC50: 5.24E+3nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
Indian Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandPNGBDBM50546162(CHEMBL4752466)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed