BDBM50547211 CHEMBL4794855

SMILES CC#CC(=O)N1CCN(CC1)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=MYTGFZAQMAJYIP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547211   

TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50547211(CHEMBL4794855)
Affinity DataEC50:  2.40E+4nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50547211(CHEMBL4794855)
Affinity DataEC50:  2.60E+4nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed