BDBM50547414 CHEMBL4751496

SMILES COC(=O)N(C)c1c(N)nc(nc1N)-n1nc(Cc2ccccc2F)c2cc(ccc12)C#N

InChI Key InChIKey=GWPPRVRHGLKKCT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547414   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50547414(CHEMBL4751496)Copy SMILESCopy InChI

Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Merck

Curated by ChEMBL

LigandBDBM50547414(CHEMBL4751496)Copy SMILESCopy InChI

Affinity DataEC50:  4.30E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL