BDBM50547430 CHEMBL4753045

SMILES CC1(C)C(=O)Nc2nc(nc(N)c12)-n1nc(Cc2c(F)ccc(F)c2F)c2cc(Cl)ccc12

InChI Key InChIKey=GTDUMDPQHXDMIF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547430   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck

Curated by ChEMBL

LigandBDBM50547430(CHEMBL4753045)Copy SMILESCopy InChI

Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Merck

Curated by ChEMBL

LigandBDBM50547430(CHEMBL4753045)Copy SMILESCopy InChI

Affinity DataEC50:  7.30E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL