BDBM50547672 CHEMBL4758571

SMILES CNC(=O)c1ccccc1Nc1nc(Nc2ccc(cc2OC)-n2cccc2C(=O)NCCO)ncc1Cl

InChI Key InChIKey=UKNPXJNVSMLUMX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547672   

TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547672(CHEMBL4758571)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of wild-type ALK (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50547672(CHEMBL4758571)
Affinity DataIC50: 13nMAssay Description:Inhibition of ALK L1196M (unknown origin) incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed