BDBM50547961 CHEMBL4777409

SMILES CCC1(O)CCCN(C1)c1nc2nc(oc2cc1NC(=O)c1coc(n1)-c1ccnc(C)c1)N1CCOCC1

InChI Key InChIKey=QXLAWCPTQRLVMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50547961   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50547961(CHEMBL4777409)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected sf9 cells using biotinylated histone H3 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed