BDBM50548533 CHEMBL4739987

SMILES CC[C@@H](C)OC(=O)C1(CC1)c1nc2c(OC)ccc(-c3ccc4C(=O)OCc4c3)n2n1

InChI Key InChIKey=URNKXCKNSGNBEE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548533   

LigandPNGBDBM50548533(CHEMBL4739987)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human PDE4D catalytic domain using cAMP and FAM-conjugated cAMP by IMAP FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50548533(CHEMBL4739987)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of PDE4D in human PBMC assessed as reduction in lipopolysaccharide-induced TNFalpha production pre-incubated for 30 mins before LPS stimul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed