BDBM50548539 CHEMBL4742661

SMILES COc1ccc(-c2cccc(c2)C#N)n2nc(nc12)C1(CC1)C(=O)OCC(C)C

InChI Key InChIKey=INYAKJWKAYBIKC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548539   

LigandPNGBDBM50548539(CHEMBL4742661)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PDE4D catalytic domain using cAMP and FAM-conjugated cAMP by IMAP FRET progressive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
LigandPNGBDBM50548539(CHEMBL4742661)
Affinity DataIC50: 31nMAssay Description:Inhibition of PDE4D in human PBMC assessed as reduction in lipopolysaccharide-induced TNFalpha production pre-incubated for 30 mins before LPS stimul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed