BDBM50548595 CHEMBL4777212

SMILES Cc1ccc(cc1C)C(=O)n1nc(nc1N)-c1ccccn1

InChI Key InChIKey=DZGOQOXWBUEYTK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50548595   

TargetProthrombin(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548595(CHEMBL4777212)
Affinity DataIC50: 57nMAssay Description:Inhibition of human coagulation factor alpha-thrombin using Boc-Val-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548595(CHEMBL4777212)
Affinity DataIC50: 91nMAssay Description:Inhibition of human coagulation factor XIIA using Boc-Gln-Gly-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548595(CHEMBL4777212)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of human uPA using Tos-Gly-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548595(CHEMBL4777212)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human coagulation factor Xa using Boc-Ile-Glu-Gly-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548595(CHEMBL4777212)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human coagulation factor XIA using Mes-dArg-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548595(CHEMBL4777212)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human kallikrein using Mes-dArg-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548595(CHEMBL4777212)
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of human plasmin using Mes-dArg-Phe-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed