BDBM50548602 CHEMBL4764774

SMILES Nc1nc(nn1C(=O)c1ccco1)-c1ccccn1

InChI Key InChIKey=KJJKEALCQGNGKZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50548602   

TargetCoagulation factor XII(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548602(CHEMBL4764774)
Affinity DataIC50: 968nMAssay Description:Inhibition of human coagulation factor XIIA using Boc-Gln-Gly-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetProthrombin(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548602(CHEMBL4764774)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human coagulation factor alpha-thrombin using Boc-Val-Pro-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of M£Nster

Curated by ChEMBL
LigandPNGBDBM50548602(CHEMBL4764774)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human coagulation factor Xa using Boc-Ile-Glu-Gly-Arg-AMC as fluorogenic substrate measured at 1 min interval for 1 hr by fluorometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed