BDBM50548708 CHEMBL4779424

SMILES CN(C)CC\C=C\c1cccnc1

InChI Key InChIKey=ZZHZSKGOOLOJFA-UHFFFAOYSA-N

Data  1 KI  15 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50548708   

TargetB2 bradykinin receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from B2 bradykinin receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from cholecystokinin receptor type A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from cholecystokinin receptor type B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from Endothelin receptor type A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from Endothelin receptor type B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from muscarinic M2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from muscarinic M3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from Histamine H3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataEC50:  732nMAssay Description:Agonist activity at alpha4beta2 nAChR in rat thalamic synaptosomes assessed as increase in 86Rb effluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from NPY2R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from Thromboxane A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from 5-hydroxytryptamine receptor 1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from 5-hydroxytryptamine receptor 2A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]nicotine from 5-hydroxytryptamine receptor 3A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50548708(CHEMBL4779424)
Affinity DataKi:  26nMAssay Description:Inhbition of [3H] nicotine binding to rat brain alpha4beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed