BDBM50549055 CHEMBL4792934

SMILES CC(=O)Nc1ncc(CN2CCC3(CCN(C3)c3cc(C)cc(C)n3)C2)s1

InChI Key InChIKey=ZCCOYDYCRSFOBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50549055   

TargetProtein O-GlcNAcase(Human)
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50549055(CHEMBL4792934)
Affinity DataIC50: 46nMAssay Description:Inhibition of OGA in HEK293 cells induced with human Tau P30IL mutant assessed as increase in O-GlcNAcylated protein levels measured after 6 hrs by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed