BDBM50549231 CHEMBL4789425

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cc(SCC(O)=O)c(O)c2ccccc12

InChI Key InChIKey=HDIHQELULSLYRT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549231   

LigandPNGBDBM50549231(CHEMBL4789425)
Affinity DataKi:  120nMAssay Description:Inhibition of Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 as substrate incubated for 30 mins followed by substrate addition and measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50549231(CHEMBL4789425)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of Bcl2 (unknown origin) using 5-FAM-Bid-BH3 as substrate incubated for 30 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed