BDBM50549241 CHEMBL4764582

SMILES COc1cc(NC(=O)c2cccc(n2)C(F)(F)F)cc2cn(nc12)C1CCN(C)CC1

InChI Key InChIKey=JSCLLHPBPYFJPK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50549241   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549241(CHEMBL4764582)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549241(CHEMBL4764582)
Affinity DataIC50: 125nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549241(CHEMBL4764582)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549241(CHEMBL4764582)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of IRAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed