BDBM50549258 CHEMBL4779374

SMILES CCS(=O)(=O)N1CC(C1)n1cc2cc(NC(=O)c3cccc(n3)C(F)(F)F)c(cc2n1)C(C)(C)O

InChI Key InChIKey=BXRSHPLJLHEUPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549258   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549258(CHEMBL4779374)
Affinity DataIC50: 57nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549258(CHEMBL4779374)
Affinity DataIC50: 256nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed