BDBM50549259 CHEMBL4799896

SMILES CC(C)(O)c1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)C1CN(C1)C(=O)CC#N

InChI Key InChIKey=HAIBYQJFNKYMOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50549259   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549259(CHEMBL4799896)
Affinity DataIC50: 37nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Zhejiang Hisun Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50549259(CHEMBL4799896)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IRAK4 in human THP-1 cells by cell based anti-inflammatory assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed