BDBM50549326 CHEMBL4784645

SMILES C[C@@H](Nc1ccn2ncc(NC(=O)N3CC[C@H](O)C3)c2n1)c1cc(F)ccc1F

InChI Key InChIKey=KDQLYPXJALLMPO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50549326   

TargetNT-3 growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50549326(CHEMBL4784645)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Trk-C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50549326(CHEMBL4784645)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of Trk-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jiangnan University

Curated by ChEMBL
LigandPNGBDBM50549326(CHEMBL4784645)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Trk-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed