BDBM50549428 CHEMBL4790584

SMILES Cc1cc(Nc2ccc(F)c(C)c2)n2nc(SCc3nc4ccccc4[nH]3)nc2n1

InChI Key InChIKey=FRGGHWYQHXLFQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50549428   

TargetATP-dependent translocase ABCB1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50549428(CHEMBL4790584)
Affinity DataIC50: 470nMAssay Description:Inhibition of ABCB1 in multidrug-resistant human SW620/Ad300 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed