BDBM50549446 CHEMBL4790690

SMILES Cc1cc(Nc2ccc(F)cc2)n2nc(SCc3cccc(c3)[N+]([O-])=O)nc2n1

InChI Key InChIKey=PZAQPAVERBGRNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50549446   

TargetATP-dependent translocase ABCB1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50549446(CHEMBL4790690)
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of ABCB1 in multidrug-resistant human SW620/Ad300 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed