BDBM50549454 CHEMBL4753848

SMILES CC(C)c1cc(Nc2ccc(F)cc2)n2nc(SCc3ccccc3)nc2n1

InChI Key InChIKey=SUNKJHCSPLQSGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50549454   

TargetATP-dependent translocase ABCB1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50549454(CHEMBL4753848)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of ABCB1 in multidrug-resistant human SW620/Ad300 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed