BDBM50549501 CHEMBL4779034

SMILES COC1CCN(CC1)c1ncnc2sc(cc12)-c1cnc(OC)c(NS(=O)(=O)c2ccc(F)cc2F)c1

InChI Key InChIKey=YHIRDNSGXDAPGS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50549501   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Peking Union Medical College

Curated by ChEMBL

LigandBDBM50549501(CHEMBL4779034)Copy SMILESCopy InChI

Affinity DataIC50: 4.80nMAssay Description:Inhibition of recombinant human full length His-tagged PI3Kalpha expressed in baculovirus expression system using PIP2 as substrate by ADP-Glo reagen...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2022
Entry Details Article
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