BDBM50549512 CHEMBL4789380

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1nc2c(ncnc2s1)N1CCCCC1

InChI Key InChIKey=MZKLUQYBZREHON-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50549512   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Peking Union Medical College

Curated by ChEMBL

LigandBDBM50549512(CHEMBL4789380)Copy SMILESCopy InChI

Affinity DataIC50: 8.80nMAssay Description:Inhibition of recombinant human full length His-tagged PI3Kalpha expressed in baculovirus expression system using PIP2 as substrate by ADP-Glo reagen...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2022
Entry Details Article
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