BDBM50550231 CHEMBL4752488

SMILES COc1ccc2[nH]cc(CCNC(=O)CN(CCCCCCNc3c4CCCCc4nc4ccc(OC)cc34)C(=O)CCCC[C@@H]3CCSS3)c2c1

InChI Key InChIKey=ZYKIOUVTAQGDKW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50550231   

TargetCholinesterase(Horse)
UBFC

Curated by ChEMBL
LigandPNGBDBM50550231(CHEMBL4752488)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of horse serum BuChE pre-incubated for 10 mins before addition of butyrylthiocholine iodide substrate and further incubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
UBFC

Curated by ChEMBL
LigandPNGBDBM50550231(CHEMBL4752488)
Affinity DataIC50: 16nMAssay Description:Inhibition of Electrophorus electricus AChE pre-incubated for 10 mins before addition of acetylthiocholine iodide substrate and further incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
UBFC

Curated by ChEMBL
LigandPNGBDBM50550231(CHEMBL4752488)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of BuChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of butyrylthiocholine iodide substrate by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
UBFC

Curated by ChEMBL
LigandPNGBDBM50550231(CHEMBL4752488)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AChE in human erythrocyte hemo-lyzates pre-incubated for 5 mins before addition of acetylthiocholine iodide substrate by Ellman's metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed