BDBM50550555 CHEMBL4437647

SMILES NS(=O)(=O)c1ccc(cc1)-c1cc(NC(=O)c2ccc(O[C@H]3CCNC3)c(c2)-c2ccc(F)c(F)c2)ccc1O[C@H]1CCNC1

InChI Key InChIKey=WMJXYRWBZGQNPC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50550555   

TargetB-cell CLL/lymphoma 9 protein(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50550555(CHEMBL4437647)
Affinity DataKi:  5.60E+3nMAssay Description:Inhibition of protein interaction between C-terminal 6x-histidine tagged full-length beta-catenin (1 to 781 residues) (unknown origin)/N-terminal bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetB-cell CLL/lymphoma 9 protein(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50550555(CHEMBL4437647)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of protein interaction between beta-catenin (unknown origin)/BCL9 in human SW480 cells transfected with beta-catenin assessed as reduction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetB-cell CLL/lymphoma 9 protein(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50550555(CHEMBL4437647)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of protein interaction between beta-catenin (unknown origin)/BCL9 in HEK293 cells transfected with beta-catenin assessed as reduction in W...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed