BDBM50550895 CHEMBL4757365

SMILES CC(=O)Nc1cc(Nc2ccc(F)c(OC(F)(F)F)c2)c2cc([nH]c2c1)C(O)=O

InChI Key InChIKey=LOVKCUUBJNRLCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550895   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50550895(CHEMBL4757365)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated for 45 mins by microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50550895(CHEMBL4757365)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of recombinant human TDO assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated for 45 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed