BDBM50550903 CHEMBL4741917

SMILES CC(=O)Nc1cc(Nc2ccc(F)c(c2)-c2ccsc2)c2cc([nH]c2c1)C(O)=O

InChI Key InChIKey=JBUPALPCHYXVLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50550903   

TargetTryptophan 2,3-dioxygenase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50550903(CHEMBL4741917)
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of recombinant human TDO assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated for 45 mins by microplate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50550903(CHEMBL4741917)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine formation using L-tryptophan as substrate incubated for 45 mins by microplat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed