BDBM50550954 CHEMBL4744898

SMILES COc1cc(\C=N\c2c(C#N)c(cn2-c2ccc(cc2)S(N)(=O)=O)-c2ccc(Cl)cc2)ccc1O

InChI Key InChIKey=ZDDJLPPEIVKQGI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50550954   

TargetCarbonic anhydrase 12(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50550954(CHEMBL4744898)
Affinity DataKi:  72nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50550954(CHEMBL4744898)
Affinity DataKi:  785nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50550954(CHEMBL4744898)
Affinity DataKi:  1.46E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50550954(CHEMBL4744898)
Affinity DataKi:  2.04E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed