BDBM50551532 CHEMBL4744709

SMILES CC(C)C[C@@H](CN[C@@H](CC(C)C)C=O)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=HIBRVPWKRQKYOQ-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50551532   

TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50551532(CHEMBL4744709)
Affinity DataIC50: 110nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50551532(CHEMBL4744709)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of caspase-like activity of human 20S proteasome beta 1 subunit using Z-nLPnLD-Glo as substrate incubated for 2 hrs followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50551532(CHEMBL4744709)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit using Z-LRR-Glo as substrate incubated for 2 hrs followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University Health Science Center

Curated by ChEMBL
LigandPNGBDBM50551532(CHEMBL4744709)
Affinity DataKd:  1.70E+4nMAssay Description:Binding affinity to immobilized human 20S proteasome beta 5 subunit by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed