BDBM50551584 CHEMBL4793264

SMILES CCC(=C(c1ccc(O)cc1)c1ccc(C=CC(=O)NCCN)cc1)c1ccccc1

InChI Key InChIKey=KJKVIJYJTOEVGA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50551584   

TargetEstrogen receptor beta(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50551584(CHEMBL4793264)
Affinity DataIC50: 3.60nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50551584(CHEMBL4793264)
Affinity DataIC50: 4.30nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50551584(CHEMBL4793264)
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50551584(CHEMBL4793264)
Affinity DataIC50: 14nMAssay Description:Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed