BDBM50551610 CHEMBL4740522

SMILES COc1ccc2[nH]cc(CCNC(=O)c3ccccc3Nc3ccccc3)c2c1

InChI Key InChIKey=MALXHVGKGSHLTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50551610   

TargetProstaglandin G/H synthase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50551610(CHEMBL4740522)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50551610(CHEMBL4740522)
Affinity DataIC50: 3.86E+4nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed