BDBM50551611 CHEMBL4789910

SMILES Oc1ccc2[nH]cc(CCNC(=O)c3ccccc3Nc3ccccc3)c2c1

InChI Key InChIKey=CFRFWENQINXUII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50551611   

TargetProstaglandin G/H synthase 1(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50551611(CHEMBL4789910)
Affinity DataIC50: 500nMAssay Description:Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50551611(CHEMBL4789910)
Affinity DataIC50: 380nMAssay Description:Inhibition of human COX2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed