BDBM50551663 CHEMBL4779315

SMILES COc1cc2nccc(Oc3ccc(NC(=O)C(OC(=O)c4ccc(F)cc4)C(C)(C)C)cc3F)c2cc1OC

InChI Key InChIKey=FVPYEAORCOKOLV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50551663   

TargetHepatocyte growth factor receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) 4:1 as substrate measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50: 19nMAssay Description:Inhibition of Ron (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50: 295nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50: 540nMAssay Description:Inhibition of Flt4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Harbin Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50551663(CHEMBL4779315)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed