BDBM50552171 CHEMBL4757567

SMILES CN1CCC(CNC2=NC(=O)\C(S2)=C\c2csc(n2)-c2ccc(OC(F)(F)F)cc2)CC1

InChI Key InChIKey=XPNXJUTYEUAHQN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50552171   

TargetSerine/threonine-protein kinase pim-1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50552171(CHEMBL4757567)
Affinity DataIC50: 9nMAssay Description:Inhibition of human PIM1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50552171(CHEMBL4757567)
Affinity DataIC50: 22nMAssay Description:Inhibition of PIM1 (unknown origin) by coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50552171(CHEMBL4757567)
Affinity DataIC50: 75nMAssay Description:Inhibition of human PIM3More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50552171(CHEMBL4757567)
Affinity DataIC50: 86nMAssay Description:Inhibition of human PIM2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50552171(CHEMBL4757567)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50552171(CHEMBL4757567)
Affinity DataIC50: 7.12E+3nMAssay Description:Inhibition of human TrkAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50552171(CHEMBL4757567)
Affinity DataIC50: 8.95E+3nMAssay Description:Inhibition of human DAPK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed