BDBM50552390 CHEMBL4741635

SMILES CC(Nc1c(Cl)cnc2ncc(cc12)-c1cnc(nc1)C(C)(C)O)c1ccccc1F

InChI Key InChIKey=MOPNWNJCNKYZFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50552390   

TargetTumor necrosis factor(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552390(CHEMBL4741635)
Affinity DataIC50: 207nMAssay Description:Displacement of fluorescent labeled probe from human recombinant His-tagged TNFalpha (77 to 233 residues) expressed in Escherichia coli preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed