BDBM50552394 CHEMBL4781182

SMILES Cc1ccc(C)c(Nc2c(C)cnc3ccc(cc23)-c2cnc(nc2)C(C)(C)O)c1

InChI Key InChIKey=HQSQJEHUENMAJY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50552394   

TargetTumor necrosis factor(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552394(CHEMBL4781182)
Affinity DataIC50: 107nMAssay Description:Inhibition of exogenous human TNFalpha in HEK-Blue-CD40L cells assessed as reduction in TNF-alpha-induced NFkappaB activation incubated for 18 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed