BDBM50552395 CHEMBL4755052

SMILES C[C@@H](Nc1c(Cl)cnc2ccc(cc12)-c1cnc(nc1)N1CCN(CC(O)=O)CC1)c1ccccc1F

InChI Key InChIKey=YAKFYPWRWQOXRK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50552395   

TargetTumor necrosis factor(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552395(CHEMBL4755052)
Affinity DataIC50: 115nMAssay Description:Inhibition of exogenous human TNFalpha in HEK-Blue-CD40L cells assessed as reduction in TNF-alpha-induced NFkappaB activation incubated for 18 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed