BDBM50552501 CHEMBL4799862

SMILES CCCCCCCCOc1ccc(COc2ccc(cc2C(F)(F)F)-c2noc(n2)[C@@H]2CCCN2C(N)=N)cc1

InChI Key InChIKey=LRMZRPHKDJKMBI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552501   

TargetSphingosine kinase 2(Human)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50552501(CHEMBL4799862)
Affinity DataKi:  400nMAssay Description:Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production using sphingosine as substrate in presence of [gamma33P]-ATP by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50552501(CHEMBL4799862)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]SIP production using D-erythro-sphingo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed