BDBM50552550 CHEMBL4754713

SMILES COc1ccc(Oc2c(Cl)cc(NC(=O)Cc3cnn(c3)S(C)(=O)=O)cc2Cl)cc1C(C)C

InChI Key InChIKey=LJTAWAVSFHPTTE-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552550   

TargetNuclear receptor ROR-gamma(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552550(CHEMBL4754713)
Affinity DataEC50:  133nMAssay Description:Agonist activity at Gal4-fused RORgammat (unknown origin) expressed in Jurkat cells by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552550(CHEMBL4754713)
Affinity DataEC50:  1.79E+3nMAssay Description:Agonist activity at human TRbeta1 CHO-K1 cells by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed