BDBM50552567 CHEMBL4779114

SMILES Oc1ccc(cc1)S(=O)(=O)NCCNc1cc(ccn1)-c1[nH]c(nc1-c1cccc(O)c1)-c1ccccc1

InChI Key InChIKey=PRUDXDBOPSYDEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552567   

TargetSerine/threonine-protein kinase B-raf(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50552567(CHEMBL4779114)
Affinity DataIC50: 32nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by HotSpot kinase ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of Science & Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50552567(CHEMBL4779114)
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant human GST-tagged full length p38a expressed in Escherichia coli expression system using Ser/Thr 04 as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed