BDBM50552614 CHEMBL4789747

SMILES Oc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1nc(NCCN2CCOCC2)nc(n1)N1CCOCC1

InChI Key InChIKey=UCZZPKDXRPXEAF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50552614   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Maternal and Child Health Hospital of Hubei Province

Curated by ChEMBL
LigandPNGBDBM50552614(CHEMBL4789747)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of PI3Kalpha (unknown origin) measured after 1 hr by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Maternal and Child Health Hospital of Hubei Province

Curated by ChEMBL
LigandPNGBDBM50552614(CHEMBL4789747)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of mTOR (unknown origin) measured after 45 mins by LANCE Ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Maternal and Child Health Hospital of Hubei Province

Curated by ChEMBL
LigandPNGBDBM50552614(CHEMBL4789747)
Affinity DataIC50: 12nMAssay Description:Inhibition of PI3Kbeta (unknown origin) measured after 1 hr by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Maternal and Child Health Hospital of Hubei Province

Curated by ChEMBL
LigandPNGBDBM50552614(CHEMBL4789747)
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3Kgamma (unknown origin) measured after 1 hr by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Maternal and Child Health Hospital of Hubei Province

Curated by ChEMBL
LigandPNGBDBM50552614(CHEMBL4789747)
Affinity DataIC50: 35nMAssay Description:Inhibition of PI3Kdelta (unknown origin) measured after 1 hr by ADP-glo plus luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed