BDBM50552672 CHEMBL4790628

SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCONC(N)=N)NC(=O)Cc1ccc(CNC(N)=N)cc1)C(=O)N[C@@H](CCONC(N)=N)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=ZMOPQXUTSHXPGZ-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50552672   

TargetProcathepsin L(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50552672(CHEMBL4790628)
Affinity DataIC50: 0nMAssay Description:Inhibition of human recombinant Cathepsin L assessed as Kinact using Z-FR-AMC as substrate incubated for 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetFurin(Human)
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552672(CHEMBL4790628)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of recombinant soluble human furin using Phac-Arg-Val-Arg-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetFurin(Human)
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552672(CHEMBL4790628)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetProthrombin(Bovine)
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552672(CHEMBL4790628)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of bovine thrombin using Tos-Gly-Pro-Arg-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552672(CHEMBL4790628)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of human factor Xa using Mes-Darg-Pro-Arg-AMC as flurogenic substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetPlasminogen(Human)
Philipps University

Curated by ChEMBL
LigandPNGBDBM50552672(CHEMBL4790628)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition pf human plasmin using Mes-Darg-Phe-Arg-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed