BDBM50552932 CHEMBL4777831

SMILES C[C@@H](NC(=O)c1ccc(Cl)cc1)c1cc2CCCN(C(=O)c3cccc(Cl)c3)c2cn1

InChI Key InChIKey=JVROLNVHOHZDJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552932   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50552932(CHEMBL4777831)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
LigandPNGBDBM50552932(CHEMBL4777831)
Affinity DataIC50: 1.60E+4nMAssay Description:Displacement of [35S]-MK499 binding to human ERG expressed in HEK293 cells incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed