BDBM50553077 CHEMBL4760340

SMILES O=C(NC1CCN(Cc2ccccc2)CC1)c1coc2ccc(OCc3ccccc3)cc2c1=O

InChI Key InChIKey=PTBGLAAUSXAMMJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50553077   

TargetAmine oxidase [flavin-containing] B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553077(CHEMBL4760340)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated with enzyme for 15 mins followed incubation with substrate for 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553077(CHEMBL4760340)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 6 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553077(CHEMBL4760340)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of recombinant human MAO- A using p-tyramine as substrate preincubated with enzyme for 15 mins followed incubation with substrate for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553077(CHEMBL4760340)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 6 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed