BDBM50553085 CHEMBL4762982

SMILES O=C(NCCC1CCN(Cc2ccccc2)CC1)c1coc2ccc(OCc3ccccc3)cc2c1=O

InChI Key InChIKey=TUTKEHICBPHHMG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50553085   

TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553085(CHEMBL4762982)
Affinity DataIC50: 370nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 6 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553085(CHEMBL4762982)
Affinity DataIC50: 5.24E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 6 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553085(CHEMBL4762982)
Affinity DataIC50: 272nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated with enzyme for 15 mins followed incubation with substrate for 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553085(CHEMBL4762982)
Affinity DataIC50: 6.72E+4nMAssay Description:Inhibition of recombinant human MAO- A using p-tyramine as substrate preincubated with enzyme for 15 mins followed incubation with substrate for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553085(CHEMBL4762982)
Affinity DataIC50: 5.24E+3nMAssay Description:Inhibition of equine serum BuchE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition and measured u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553085(CHEMBL4762982)
Affinity DataIC50: 370nMAssay Description:Inhibition of electric eel AchE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition and measured upto ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553085(CHEMBL4762982)
Affinity DataIC50: 272nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated for 15 mins in dark followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed