BDBM50553238 CHEMBL4750343

SMILES COc1ccc(cc1OC)C1Nc2c(ncn2-c2ccc(N3CCN(C)CC3)c(c2)[N+]([O-])=O)C(=N1)C(N)=O

InChI Key InChIKey=GREQUBMKQXGAHX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50553238   

TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553238(CHEMBL4750343)
Affinity DataIC50: 236nMAssay Description:Inhibition of EGFR (unknown origin) using Tyrosine 4 peptide and ATP as substrate incubated for 1 hr by Z'-lyte kinase assay based UV-VIS spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553238(CHEMBL4750343)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK4/Cyclin D3 (unknown origin) using Rb protein as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553238(CHEMBL4750343)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin) using Rb protein as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553238(CHEMBL4750343)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) using Rb protein as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553238(CHEMBL4750343)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) using Ser/Thr 12 peptide as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed