BDBM50553427 CHEMBL4741954

SMILES Cc1nnc(Nc2nccc(n2)-c2ccc(CNC(=O)c3cnc(s3)C(C)(C)C)c(C)c2)s1

InChI Key InChIKey=QRSVEFILWKCRMU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50553427   

TargetTyrosine-protein kinase BTK(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50553427(CHEMBL4741954)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human full-length N-terminal His6-tagged BTK expressed in baculovirus infected Sf21 insect cells using fluorescein-labeled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed